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Natasha_4902
#1 Posted : Saturday, August 08, 2020 6:46:18 PM
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Hi,

What are the similarities and differences between the signal transduction of cardiac, skeletal, and smooth muscles? For example, do smooth and cardiac muscle also have a sarcoplasmic reticulum with Ca2+ and use tropomysin and troponin?

Thank you
INSTR_Katerina_102
#2 Posted : Monday, August 10, 2020 5:09:07 AM
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Hi Natasha,

Do smooth and cardiac muscle also have a sarcoplasmic reticulum with Ca2+?

Cardiac and skeletal muscle have SR with Ca2+, and while it is known as the ER for smooth muscle cells, smooth muscle cells also use it to store Ca2+ in a similar fashion.


Do cardiac and smooth muscle cells also use tropomysin and troponin?


Tropomyosin and Troponin can also be found in cardiac muscle. I think there are some minor variations between cardiac and skeletal muscle, but for the level of the MCAT I would treat them as largely similar processes. \

Smooth muscle cells are kind of the odd one out here - they don't contain troponin but instead calmodulin.

I hope this helps,

Katt
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