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Josh_4080
#1 Posted : Saturday, June 20, 2020 3:55:03 PM
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I am seeing a lot of E1 and E2 reaction talk in Altius tests but can't find anything about them in our reactions lecture. I was wondering what these are and how I should think about them and relate them to our previous reactions spoken about? This is referring to questions in Altius Test 3 - Question 49 is a good one. In the answer explanation video it speaks about E1 vs. SN1.

Thanks!
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INSTR_Katerina_102
#2 Posted : Sunday, June 21, 2020 5:52:29 PM
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https://ibb.co/yfNV4dm This is a basic comparison of all the mechanisms of SN2/SN1/E2/E1.

E2 stands for elimination (2nd order) and essentially is a reaction where a base eliminates a leaving group forming an alkene. It often competes with SN2 reactions as many nucleophiles are also good bases.

E1 stands for elimination (1st order) and is a reaction where a hydride on a carbocation is plucked off by a weak base, leaving an alkene. Usually E1 reactions look like SN1 reactions but they have no good nucleophile in solution.

This is something you could consider asking further for in person office hours as new mechanisms can get clarified a bit more quickly with verbal explanations.
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Josh_4080
#3 Posted : Monday, June 22, 2020 5:23:34 PM
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Thank you!
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INSTR_Radhika_42
#4 Posted : Tuesday, June 23, 2020 11:19:10 PM
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Hello!

It may also be helpful to note that E1 and E2 are not directly testable on the MCAT. You will not have to know the mechanisms as per the AAMC.
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