Welcome Guest Search | Active Topics |

Tag as favorite
PTH
Options
Previous Topic Next Topic
Moiz_6047
#1 Posted : Sunday, June 06, 2021 11:37:01 PM
Rank: Advanced Member

Groups: Registered
Joined: 5/3/2021
Posts: 51

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Why Does PTH Activate Vitamin D? I thought that vitamin D causes bone synthesis and PTH promotes osteoclast activity? Thanks!
Back to top
Report?
INSTR_Kennedy_135
#2 Posted : Monday, June 07, 2021 2:19:50 PM
Rank: Advanced Member

Groups: Registered
Joined: 5/14/2021
Posts: 56

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hello,

Vitamin D is inactive until the kidney converts it to an active form with 1,a-OHas. PTH gets released when there is low serum Ca (someone has osteoporosis. It is needed to activate 1,a-OHase in the kidney. Activated Vitamin D allows the kidney to reabsorb more Ca (bring up serum Ca levels) and secrete more P.

PTH also acts on the gut to increase Ca and P reabsorption from the diet and acts on the bones for osteoclasts to release P and Ca (both these elements are in the bone and you cannot release just one, the bone gets universally broken down). Overall all these actions increase serum Ca levels and you would get feedback on the parathyroid to shut off PTH.
Back to top
Report?
Users browsing this topic
Guest
Tag as favorite
You cannot post new topics in this forum.
You cannot reply to topics in this forum.
You cannot delete your posts in this forum.
You cannot edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.

Clean Slate theme by Jaben Cargman (Tiny Gecko)
Powered by YAF | YAF © 2003-2009, Yet Another Forum.NET
This page was generated in 0.073 seconds.