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Location of Autosomal/Sex Linked Genes
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Moiz_6047
#1 Posted : Saturday, July 03, 2021 12:11:43 AM
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1) Is there a difference in the location for autosomal/sex linked genes?

2) If I wanted to manipulate a gene involved in a metabolism pathway (in the mitochondria - beta oxidation for instance) would I make changes in the nucleus or mitochondira?
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INSTR_Molly_129
#2 Posted : Saturday, July 03, 2021 8:36:31 PM
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Hi Moiz,

1) Autosomal genes are contained in chromosomes #1-22 and sex-linked genes are for the majority a part of the X chromosome.

2) This would depend. Actually throughout time, we have found that a lot of the mitochondrial genes have moved into the nucleus, given that it is likely that the mitochondria is exposed to many reactive-oxygen species from cellular respiration that would result in high-mutagenic rates. Although the theory is proposed, to my knowledge there has not been any proof. So all-in-all, it would really depend.

Hope this helps, cheers and happy studying

Molly
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