Welcome Guest Search | Active Topics |

Tag as favorite
AAMC section bank bio q19
Options
Previous Topic Next Topic
Lydia_5054
#1 Posted : Wednesday, July 14, 2021 3:20:20 PM
Rank: Member

Groups: Registered
Joined: 5/3/2020
Posts: 29

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hi

I was just wondering how we go about this question with the knowledge of retroviruses. If we have our mRNA, then to find the original viral genome, wouldnt we just get the cDNA of that strand? im just confused because all i know is that it would be the reverse central dogma so from mrna to dna so i just don't get whats happening here.
Back to top
Report?
INSTR_Kennedy_135
#2 Posted : Tuesday, July 20, 2021 11:36:41 PM
Rank: Advanced Member

Groups: Registered
Joined: 5/14/2021
Posts: 56

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Yep you are on the right track!

With a retrovirus you can reverse transcription, so you would go from mRNA to (c)DNA. The MRNA will be digested by reverse transcriptase, and a complimentary strand to the mRNA will be made= cDNA. Then DNA polymerase will help the cDNA double-stranded. The cDNA is the DNA without any introns as it come from the mRNA that already had them removed.

It still follows the central dogma, just with the adjustment of no introns so you refer to it as cDNA.
Back to top
Report?
Users browsing this topic
Guest (2)
Tag as favorite
You cannot post new topics in this forum.
You cannot reply to topics in this forum.
You cannot delete your posts in this forum.
You cannot edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.

Clean Slate theme by Jaben Cargman (Tiny Gecko)
Powered by YAF | YAF © 2003-2009, Yet Another Forum.NET
This page was generated in 0.084 seconds.