Welcome Guest Search | Active Topics |

Tag as favorite
Involvement of R-groups in secondary structure
Options
Previous Topic Next Topic
Lauren_6408
#1 Posted : Thursday, May 27, 2021 3:50:33 AM
Rank: Member

Groups: Registered
Joined: 5/16/2021
Posts: 15

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hi. I know that secondary protein structure is stabilized with hydrogen bonds between the amino group and carbonyl groups but I was wondering if the R-group has a role in determining whether it will be an a-helix or b-sheet.
Back to top
Report?
INSTR_Kennedy_135
#2 Posted : Thursday, May 27, 2021 6:10:55 PM
Rank: Advanced Member

Groups: Registered
Joined: 5/14/2021
Posts: 56

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hello,

Whenever you think about secondary structure you should always associate it with hydrogen bonds. It is the main stabilizer and that is what you should know for the MCAT.

The amino acid group can affect the stability and characteristics of the helix. For example in sickle cell disease, there is a swap of amino acids and it essentially breaks the secondary structure. For other molecules like collagen smaller amino acids make for a tighter helix which helps with stability for this is all just for your interest.

Kennedy
Back to top
Report?
Users browsing this topic
Guest
Tag as favorite
You cannot post new topics in this forum.
You cannot reply to topics in this forum.
You cannot delete your posts in this forum.
You cannot edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.

Clean Slate theme by Jaben Cargman (Tiny Gecko)
Powered by YAF | YAF © 2003-2009, Yet Another Forum.NET
This page was generated in 0.068 seconds.