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SRINIJA_828
#1 Posted : Friday, August 06, 2021 3:05:00 AM
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Hey guys! I am reviewing all the biochem pathways and I just realized that in TCA succinate turns into fumarate when FAD+ turns into FADH2 but in ETC succinate turns into fumarate when FADH2 turns into FAD+. But I don't understand why is this the case? Any help would be appreciated. Thank you
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INSTR_Shinthujah_131
#2 Posted : Friday, August 06, 2021 5:25:55 PM
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Hi Srinija,

In both TCA cycle and ETC, succinate is oxidized to fumarate and in doing so you go from FAD+ to FADH2. The FADH2 is oxidized to FAD+ in the ETC, to give those electrons to complex II.

Hope this helps! :)
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