Welcome Guest Search | Active Topics |

Tag as favorite
Amino acids' Molecular Weight
Options
Previous Topic Next Topic
Pavithra_6147
#1 Posted : Wednesday, February 24, 2021 4:52:08 PM
Rank: Newbie

Groups: Registered
Joined: 2/15/2021
Posts: 2

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hello,

Question 21 of the AAMA biology section bank required us to approximate the molecular weight of an inactive tetramer of Integrase (IN). In the passage, it was given that IN is composed of 288 amino acids. I knew that this was an important piece to finding the weight of IN, but I didn't know how to apply it. In the explanation, it said that an amino acid has moelcular weight of 110 Da. I was able to fingure out how to get the weight of IN after this, but are we expected to know that an AA weighs 110 Da?
Back to top
Report?
raquel
#2 Posted : Wednesday, March 17, 2021 11:42:22 PM
Rank: Administration

Groups: Administrators
Joined: 6/6/2011
Posts: 20

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hi there,

Single letter codes of amino acids are super important for the MCAT - the passage states that there are conserved residues (which is a fancy way of saying amino acid) and the D64 is the key - this means that at position 64 there is a D amino acid and D is the single letter code for aspartate. That's how you know.

And the substitution that would be the least likely to affect the function would be switching to an amino acid with similar properties to the original. So because D is polar charged acidic then switching to another polar charged acidic like glutamic acid would be unlikely to cause a big shift in the protein.
Back to top
Report?
INSTR_Kennedy_135
#3 Posted : Tuesday, July 20, 2021 8:42:21 PM
Rank: Advanced Member

Groups: Registered
Joined: 5/14/2021
Posts: 56

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Yes good job team :)
Back to top
Report?
Users browsing this topic
Guest
Tag as favorite
You cannot post new topics in this forum.
You cannot reply to topics in this forum.
You cannot delete your posts in this forum.
You cannot edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.

Clean Slate theme by Jaben Cargman (Tiny Gecko)
Powered by YAF | YAF © 2003-2009, Yet Another Forum.NET
This page was generated in 0.079 seconds.