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Questions based on Biology 1: Molecules Study Guide lesson 1 and 3 information
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Michelle_6624
#1 Posted : Friday, May 07, 2021 8:45:25 AM
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1.Does oxidation of fatty acids cause the release of their energy?
2.Why are asparagine and glutamine not considered basic? And do they participate in acid base chemistry?
3.In what condition does the addition of water cause peptide bonds to break within a polypeptide?
4. In the study guide it says that water pushes hydrophobic R groups away which increase entropy which is highly favourable but isn't increase entropy bad?
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Anjali_5681
#2 Posted : Monday, May 10, 2021 7:46:53 PM
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Hi Michelle,

1. Yes; beta oxidation of fatty acids results in release of FADH2, NADH, and acetylCOA, which will result in production of ATP from oxidative- and substrate-level phosphorylation :)

2. The carbonyl group situated next to the amine group makes it have a slightly lower pKa than the basic amino acids we work with. Therefore, it is neutral, and will not participate in acid-base chemistry for our purposes.

3. Usually, with the help with enzymes. On its own, peptide bonds require YEARS to break.

4. If we look at the Gibbs energy equation, you will find that it would be favourable (negative delta G) if the entropy was large and positive. Increase entropy is associated with "disorder" but in this case, disorder is the natural state of things, and what it would want to move towards.

Hope this helps!
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