Welcome Guest Search | Active Topics |

Tag as favorite
Biology 1 EK ICE 2 Question 27
Nicole_5521
#1 Posted : Sunday, May 30, 2021 11:32:37 PM
Rank: Advanced Member

Groups: Registered
Joined: 4/30/2020
Posts: 58

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hello,

I'm confused about Question 27 from ICE 2 Passage 1 in the Biology 1 EK book.

First, 5aza-dC is a drug that demethylates and then decreases gene expression of the CD3Z gene. Is this just inferred from the passage/question information?

Second, how can you tell that increased methylation in repressor regions leads to increased expression? Does this happen with all repressor regions? Where does this information come from?

Thanks!
INSTR_Molly_129
#2 Posted : Monday, May 31, 2021 4:55:10 PM
Rank: Advanced Member

Groups: Registered
Joined: 5/23/2021
Posts: 64

Thanks: 0 times
Was thanked: 0 time(s) in 0 post(s)
Hi Nicole,

The text for Experiment 2 indicates that 5aza is a demethylating drug.
As for the increased expression, this was derived from the question stem and information from Experiment 2 passage. It states that 5aza is a demethylase, so it decreases methylation.
From the stem, we are told that increased demethylation decreases expression, so in other words, decreased methylation, decreases expression. So, it would stand that D would be the correct answer.

Hope that helps, and happy studying!

Cheers,

Molly
Users browsing this topic
Guest
Tag as favorite
You cannot post new topics in this forum.
You cannot reply to topics in this forum.
You cannot delete your posts in this forum.
You cannot edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.

Clean Slate theme by Jaben Cargman (Tiny Gecko)
Powered by YAF | YAF © 2003-2009, Yet Another Forum.NET
This page was generated in 0.087 seconds.