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#1 Posted : Tuesday, August 03, 2021 4:19:18 AM
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83) For this question I don't understand why Insulin is not the correct answer. I understand that there would be high levels of glucose leading to lots of insulin, but wouldn't this be a good thing as the body would be able to absorb glucose? For glucagon release, glucose would be present a lot in the blood and therefore this would be a bad thing as the body wouldn't absorb the glucose? Would appreciate some help on the logic here.

88) Because it is a synthetase wouldn't it increase levels of Succinyl CoA?
#2 Posted : Friday, August 06, 2021 7:44:07 PM
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Hi Moiz,

83) The last paragraph of the passage illustrates the heightened problem that arises in infants born to poorly controlled diabetic mothers. These infants have high levels of insulin in the blood even after glucose from the blood is depleted. The passage talks about the importance of glucose release from the liver in order to maintain blood glucose levels and prevent brain injury. Insulin triggers the absorption of glucose from the blood, but if there is no more glucose in the blood (as what happens in these babies after 70 mins) insulin is no help. We need glucagon to trigger release of glucose into the blood to prevent brain injury.

88) Succinyl-CoA synthetase catalyzes the conversion of succinyl-CoA to succinate and in the process producing GTP from GDP. So if we have increased activity of the enzyme we will get more end products of the reaction, a.k.a, succinate and GTP.

Hope this helps :)
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